Cell Cycle Heterogeneity Can Generate Robust Cell Type Proportioning
نویسندگان
چکیده
منابع مشابه
Dependence of cell-type proportioning and sorting on cell cycle phase in Dictyostelium discoideum.
The relationship between the cell cycle phase of vegetative amoebae and prestalk and prespore differentiation in the slug stage were investigated in the slime mould Dictyostelium discoideum. Cells were synchronized by release from the stationary phase. Samples were taken at various times during the course of a synchronous cell doubling, fluorescently labelled and mixed with cells of random cell...
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The spatial patterning of prestalk and prespore cells in the slug arises from the differential sorting of newly differentiated cell types as the mound forms. This pattern is highly organized along an anterior-posterior axis and is constant irrespective of the size of the organism. Cell-type differentiation is plastic until late in development. A change in the ratio of cell types resulting from ...
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The human leukaemia virus HTLV-1 expresses essential Background accessory genes that manipulate the expression, splicing and transport of viral mRNAs. Two of these genes, and , also promote proliferation of the tax hbz infected cell, and both genes are thought to contribute to oncogenesis in adult T-cell leukaemia/lymphoma. The regulation of HTLV-1 proviral latency is not understood. on...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2018
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2018.09.023